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Pharmaceutical use in the Marine Aquarium

This blog entry was inspired by another one of the interesting seminars that I attended during this years MACNA conference, a seminar by Author and Hobbyist Mike Paletta “Pharmaceuticals & Marine Aquaria”. Mike’s presentation was based upon medications and treatments that have origins in other disciplines that have found their way into use for the marine aquarium.

Some of the medications and treatments that Mike spoke about have been used in the aquarium trade for many years, such as Metronidazole and Erythromycin.
Metronidazole was developed for use in human and veterinary medicine, and is used to treat a wide range of bacterial and parasitical diseases. Metronidazole is available in the aquarium hobby from a number of manufacturers, as either a lone agent (like Thomas Lab’s Fish-Zole, Aquarium System’s Hex-Out, or Seachem’s Metronidazole), or as an ingredient in more broad spectrum medications (like API’s General Cure, Jungle Lab’s Hole-N-Head Guard and Parasite Clear) Paletta focused upon the use of Metronidazole as a method for removing intestinal parasites in newly acquired fish. Intestinal parasites are a common problem in wild caught fish. Fish are not usually fed very much as they are moved from collector, to holding station, to export, to your local store, in order to reduce waste and maintain water quality. During this time fish will start to eat feces of other fish that they are being held with, so if any of the wild fish have internal parasites, then they spread rapidly.
Feeding new fish with Metronidazole soaked foods during quarantine is the best way to rid your new fish of internal pests, and to prevent infecting the fish in your display. Jungle Labs Anti-Parasite Medicated Food and Blue Lagoon Anti-Parasite Marine Gel Food are commercially available food that is pre-treated with Metronidazole and well work well with fish that will eat these forms of food. For finicky eaters, soak the food of choice with medication prior to feeding. This works well with most food types, including fresh, frozen and prepared foods. Internal parasites may have no outward symptoms. Long term problems such a reduced growth and inability to gain weight with heavy feeding may be the only signs of infestation.
Erythromycin is an antibiotic that has been used for many years in many medical disciplines for the treatment of bacterial infections. Erythromycin has been used successfully for the treatment of bacterial infections in the aquarium trade as well, and is available from several sources ( like Mardel’s Maracyn and API’s E.M. Erythromycin)
Paletta talked about a less common use for Erythromycin (EM) is to aid in the combat of Slime algae in the marine aquarium, one which I have used successfully many times. Slime algae is a rapid growing, and potentially dangerous problem in the aquarium. Severe outbreaks can grow quickly and smother everything in your aquarium. Slime Algae is a simple life form, a bacterial algae complex, which thrives in high nutrient conditions like overfed, overstocked, or dirty aquariums. Small outbreaks should be taken care of by improving water quality, increasing water flow, and physical removal by siphoning. In severe cases the use of EM can be really helpful. EM will rapidly kill slime algae in the aquarium, and help get your aquarium free from the problem. EM is not a miracle cure for slime algae, if measures are not taken to improve water quality, then the slime will return. EM should only be used in conjunction with improved husbandry habits.

The portion of Mike’s presentation that I found most interesting was the somewhat experimental use of some Veterinary drugs to combat pests in the reef aquarium. With the proliferation of the reef aquarium hobby, and the abundance coral propagating hobbyists over the last several years, a number of previously obscure pests are becoming more and more common within the trade.

Red Bugs (Tegastes acroporanus) have become alarmingly common in the propagated coral industry. These barely visible little crustaceans can rapidly reproduce, and decimate many species of Acropora corals very quickly. Treatments have been developed using Interceptor (Milbemycin oxime), a prescription de-worming medication for dogs and cats, which you have to get from your veterinarian. Several different protocols have been developed for treatment with interceptor, if you do a web search on the topic you can find a treatment plan that best suits your situation. Before consulting with your veterinarian about obtaining Interceptor, it may be a good idea to print out some articles about this new alternative use of the drug. This is not a well known alternative use for the drug, and you may get some resistance if your Vet has not come accross other requests for this use in the past.

Another reef pest that is becoming more prevalent in the hobby is the Acropora Eating Flat Worm (AEFW). These nearly invisible, translucent, flatworms attack only Acropora species corals, and are very difficult to detect (other than dead acropora). A good method that Mike uses for detection is to use a turkey baster to shoot a jet of water in and around colonies that are suspected to have AEFW, if they are present, you will dislodge some of them and see tiny translucent discs fly off the coral. There are several commercially available flat worm treatments available to the hobby, such as Salifert’s Flat Worm Exit, and Tropic Marin’s Pro-Coral Cure.
Mike Paletta spoke about a relatively new treatment for AEFW that has been developed using Levamisol, a drug commonly used as a pig de-wormer that is available through farm supply stores, or your veterinarian. Again, several protocols have been developed for the use of Levamisol against AEFW, so do some research and choose a method that best suits your situation.

An interesting side story of Mike’s presentation was one of his natural approaches to limiting parasites in his display aquariums. He actually trains fish to eat parasites from coral. He accomplishes this while he is quarantining his fish for introduction into his aquarium. The fish he chooses are natural predators of the parasites, in this case I believe they were 6-line wrasses, which he trains to select for the parasites and actively hunt them. While in quarantine he introduces corals that he knows have flatworms, and frees the worms from the coral using a turkey baster, at the same time he limits the fishes other options for food, so that they are forced to eat the flatworms. After “training” the wrasses this way for several weeks the fish start to aggressively hunt out the flatworms for a meal. Once the fish have finished quarantine, they are introduced into the display aquarium and continue to actively hunt for parasites. Pretty neat trick!

Hope that you found this as interesting as I did, until next time

Dave

Quarantine: Protect Your Display Aquarium

A quarantine tank is simply a small aquarium that is set up for the purpose isolating a fish, or fishes, from your display aquarium. Quarantine tanks are inexpensive and easy to set up, and are an investment in protection for your display aquarium.

Parasites, injury, and infectious disease are an unfortunate, and unavoidable, aspect of the aquarium hobby. One of the main purposes of a quarantine tank is to hold new fish purchases in an isolated tank that allows for easy observation. If the fish should show signs of parasites or other infections you can medicate with no risk of infecting the fish in your main tank. If you have invertibrates, or live plants in your display, you are severely limited in your choices of effective medications, not introducing pathogens is your best defense. A quarantine tank also gives new fish an opportunity to get used to processed food without having to compete with your established fishes that most likely are aggressive eaters. Another benefit of a quarantine tank is that it also gives you somewhere to put injured or aggressive fish that you may need to remove from your display.

For most fish an aquarium of 10- 20 gallons will be fine, obviously larger fish or large numbers of fish will need a lager aquarium. You do not need to get fancy with your quarantine tank, a basic set-up is all that is required. A small power filter or air powered sponge filter, a heater, and standard aquarium light is all you need. A bare bottom aquarium works best, however something for the fish to hide in is important. A small cave constructed with rocks, some artificial plants, or a length of PVC tubing is recommended.

Quarantine of new fish should last for at least 21 days, this allows for extended observation, and for any parasites that may be present to complete their life cycles. If after 21 days there has been no sign of parasites or disease it is safe to acclimate and introduce your new fish to its permanent home with minimal risk of introducing any pathogens into your display. If at any point during quarantine you suspect there may be a problem with your fish, and you decide to medicate, your quarantine “clock” must be reset and you should start the 21 day period over again. Many parasites have multiple life stages, most medications are only effective against specific stages. For this reason, only an extended exposure to medication is truly effective against many parasites. This is also why some parasitical problems seem to come and go, the parasite may only become visibly apparent at certain life stages, although they were there “hiding” all along.

Controlled feeding is another important function of a quarantine tank. Wild caught fish can be very slow to acclimate to prepared foods, and may be very timid towards accepting new types of foods. Without competition new fish get a chance to adjust at their own pace, allowing them to compete once they are ready for the display aquarium. Use of appetite enhancers, like garlic, can also aid in training finicky fish to accept new foods.

There a few things that you can do to make setting up your quarantine tank fast and easy. You do not need to keep your quarantine tank running when not needed if you are limited on space. When needed, fill your quarantine tank with water from your display, this accomplishes a water change in your display, as well as gets you started with conditioned water in your quarantine tank. Another good trick is to keep your sponge filter, or cartriges from your power filter in your display tank. this keeps them colonized with bacteria and you will not have to worry about cycling your quarantine tank if you need it in a hurry. This is very easy to do if you use a wet dry filter on your display, simply hide them in the sump untill they are needed. You can set up an instant established quarantine system in just a few minutes if you plan for it (wouldn’t it be nice if your display was that easy)

Protect your display, you have put too much time, effort, and expense into your aquarium to put it at risk. A little patience and prevention will save you a lot of stress and disappointment.

Dave